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Red and Near-Infrared to help Nerve Regeneration

Red and Near-Infrared to help Nerve Regeneration

Nerve damage is one of the most challenging conditions to treat. Whether caused by injury, surgery, diabetes, or chronic illnesses, damage to peripheral nerves often leads to pain, numbness, tingling, and impaired function. Unlike skin or muscle, nerve tissue regenerates very slowly, and in some cases, healing is incomplete. Traditional treatments often focus on managing symptoms rather than repairing the underlying damage.

In recent years, however, there has been growing interest in a non-invasive approach that may support the body’s ability to repair nerve tissue: red and near-infrared (NIR) light therapy, also known as photobiomodulation (PBM). Studies are beginning to show that PBM can stimulate cellular repair processes, improve circulation, and enhance recovery in nerve-related conditions.

So, how does this work — and what does the science say?

How Red and Near-Infrared Light Affect Nerve Cells

Both red light (around 630–660 nm) and near-infrared light (around 810–850 nm) penetrate tissues and are absorbed by mitochondria, the “powerhouses” of cells. Specifically, they target an enzyme called cytochrome c oxidase, which is part of the mitochondrial respiratory chain. When stimulated by these wavelengths, mitochondria produce more ATP (adenosine triphosphate) — the energy currency of the cell (NIH).

In nerve cells, this extra energy allows for:

  • Axonal repair: Damaged axons (the long projections of neurons) can regrow when energy demands are met.
  • Myelin regeneration: Light therapy may support the repair of myelin, the protective sheath around nerves that is critical for fast and accurate signal transmission.
  • Protein synthesis: Increased ATP fuels the creation of structural proteins needed for nerve repair.

In short, light therapy helps “recharge” injured nerves so they can carry out the demanding process of repair.

Reducing Oxidative Stress and Inflammation

Nerve injury often creates an environment of oxidative stress, where excessive reactive oxygen species (ROS) damage cellular components. Photobiomodulation helps normalize ROS levels by making mitochondria more efficient. This not only protects neurons but also reduces secondary damage that can occur after the initial injury.

In addition, light therapy reduces inflammatory cytokines — signalling proteins that can prolong pain and impair healing. By calming the inflammatory response, PBM creates a more favorable environment for regeneration. Research in the Journal of Neurotrauma found that NIR therapy not only reduced oxidative stress but also improved functional recovery after nerve injury (PubMed).

Stimulating Neurotrophic Factors

One of the most promising findings is that red and NIR light increase levels of neurotrophic factors. These are proteins that guide nerve growth, survival, and function. Among the most important are:

  • Nerve Growth Factor (NGF): Promotes survival and growth of sensory and sympathetic neurons.
  • Brain-Derived Neurotrophic Factor (BDNF): Supports synaptic plasticity, learning, and repair.

A study published in Neuroscience Letters found that PBM increased expression of BDNF and NGF in animal models, leading to enhanced axon regeneration and functional recovery (NIH).

This means that light therapy doesn’t just provide energy; it also helps activate the genetic and molecular programs necessary for nerves to rebuild themselves.

Improving Circulation and Nutrient Delivery

Nerves, especially peripheral nerves, have limited blood supply compared to other tissues. Poor circulation can slow healing and leave damaged nerves starved of oxygen and nutrients. Near-infrared light penetrates deeper than red light and stimulates nitric oxide release, which relaxes blood vessels and improves microcirculation.

A study in Lasers in Surgery and Medicine demonstrated that animals treated with NIR after nerve injury had faster functional recovery and improved nerve conduction velocity compared to controls (PubMed). Improved blood flow is key not only for repair but also for clearing out metabolic waste products that accumulate in injured tissues.

Evidence from Clinical and Preclinical Studies

While much of the research has been done in animal models, the results are encouraging - and early human studies are beginning to confirm the benefits.

  • Peripheral nerve injury: Animal studies show that PBM accelerates axonal regrowth and improves recovery of motor and sensory function.
  • Carpal tunnel syndrome: Clinical trials using NIR light have reported reductions in pain and improvements in grip strength and nerve conduction (PubMed).
  • Diabetic neuropathy: Studies suggest that PBM reduces pain and numbness while improving quality of life for patients with diabetic nerve damage.
  • Post-surgical nerve recovery: Patients treated with red/NIR light after surgery have shown reduced pain, less inflammation, and better long-term functional outcomes.

Although more large-scale clinical trials are needed, the existing data strongly suggest that photobiomodulation is a safe and effective adjunct therapy for nerve regeneration.

What Patients Report

Beyond the lab, many people using red and near-infrared therapy devices report improvements such as:

  • Reduced tingling and numbness
  • Decreased nerve pain
  • Improved muscle activation in affected areas
  • Better coordination and grip strength

While individual results vary, these reports align with the physiological mechanisms demonstrated in research.

Suggested Protocol for Nerve Regeneration (Using the Kivo Elite Panel)

If you are considering red and NIR light therapy at home, consistency is key. Nerve healing is slow, and results are usually seen over weeks to months. A commonly recommended protocol is:

  • Wavelength: Red + Near-Infrared
  • Brightness: High (Level 5 on Kivo Elite Panel)
  • Pulse: 40 Hz (associated with neurological repair and brain wave entrainment)
  • Duration: 15–20 minutes per affected area
  • Frequency: 5–7 times per week
  • Treatment Length: At least 8–12 weeks, longer for chronic conditions

This can be used alongside conventional treatments such as physical therapy, medications, and lifestyle interventions. Always consult a healthcare provider before starting new therapies, especially if you have a medical condition.

For more Light Therapy Treatment Protocols, visit our help site: https://help.myKivo.com

Why This Matters

Nerve damage can be life-changing, affecting mobility, sensation, and independence. Traditional medicine often offers limited solutions beyond pain relief. Light therapy represents a shift — instead of masking symptoms, it seeks to help the body heal itself.

As the research base expands, red and near-infrared therapy may become a standard part of nerve rehabilitation protocols, both in clinics and at home. Devices like the Kivo Elite Panel make it possible to access this promising therapy safely and consistently.

For those dealing with nerve injuries, neuropathy, or post-surgical recovery, photobiomodulation offers real hope: faster healing, less pain, and a better chance of regaining function.